Updated June 2026 · Verified against Government of Ontario guidelines
Grant Provincial Active

Life Sciences Scale-up Fund (LSSUF)

Government of Ontario
Maximum Funding
Up to 33% of costs, to a max of $2.5...
2026 intake open June 22 to Aug 4, 2026. Confirm on ontario.ca.
Visit Official Program →
Difficulty
Hard
Payment
Varies
Trend
Stable
First-Timers
Co-Funding
33%
Life Sciences Scale-up Fund (LSSUF) provides Up to 33% of costs, to a max of $2.5 million. Provides financial support to help small-to-medium sized life sciences enterprises (SMEs) in Ontario scale up, commercialize new products, and build domestic manufacturing capacity. The program covers up to 33% of eligible costs. Applications are accepted 2026 intake open June 22 to Aug 4, 2026. Confirm on ontario.ca..
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Eligibility & Details

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Program Description

Provides financial support to help small-to-medium sized life sciences enterprises (SMEs) in Ontario scale up, commercialize new products, and build domestic manufacturing capacity.

Eligibility Requirements

  • For-profit SME headquartered in Ontario
  • Must be in the human health sciences industry
  • Must have between 5 and 500 employees
  • Must have at least two years of operations
  • Project must support scale-up, new product commercialization, or domestic manufacturing capacity
Provinces
Industries
Business Stage
Growth Expansion

Quick Assessment

Difficulty
Hard
Competition
High
First-Timer
Not rated

Funding Details

Amount
Up to 33% of costs, to a max of $2.5 million
Type
Grant
Level
Provincial
Co-Funding
Up to 33% of eligible costs
Deadline
2026 intake open June 22 to Aug 4, 2026. Confirm on ontario.ca.

Program Scorecard

Competition, effort, and approval at a glance

Hybrid
Competition
High
Effort
Varies
Approval
Varies
Accessibility
--/5
Competition
--/5
Approval Rate
--%
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How to Win

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Insider Tip

The program rewards companies that are clearly past the prototype stage and moving into commercial manufacturing. The scoring heavily weights job creation (both quantity and skill level), biomanufacturing/supply chain alignment, and a credible regulatory timeline. Engage a Ministry Business Advisor before applying — they provide informal feedback and signal whether your project aligns with the current intake priorities. The stacking restriction (no other Ontario provincial grants for same project) means you must choose LSSUF over any conflicting Ontario programs. Secure your 67% matching financing BEFORE applying — the application requires evidence of financing in place by project start.

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Rejection Pitfalls 11

  • Insufficient operational history (under 2 years, or financial statements not audited/reviewed)
  • Ineligible industry (food sciences, animal health, and non-human-health applications are excluded)
  • Pre-prototype stage — must have working prototype or have commenced commercial production
+8 more pitfalls
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Success Profile

Commercial-stage life sciences SME (5–500 employees, 2+ years operating) with FDA or Health Canada approval achieved or clearly underway. Manufacturing or scale-up project with defined capital and labour costs. Strong job creation story (both retention and net-new high-skilled positions). Ontario-headquartered with plans to expand domestic production capacity. Not a startup — program targets companies in growth/expansion stage with proven revenue.

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Application Playbook

Step-by-step process, required documents, and expenses

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Required Documents 10

Completed TPON application form (signed)
Articles of Incorporation or Limited Partnership Agreement
Two years of audited or accountant-reviewed financial statements
Contractor/vendor quotes for all eligible project costs
Letter of financial attestation from senior management signing authority
Corporate family tree (parent companies, subsidiaries, affiliates)
Ontario Tax Compliance Verification number
Evidence of IP protection steps
Evidence of working prototype or small-scale commercial production
Documentation of regulatory approval pathway and timeline

Deadline Notes

A 2026 intake is open June 22 to Aug 4, 2026 (confirm on ontario.ca). The program's first intake ran Jan 20 to Mar 3, 2025.

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Funding Stack Strategy

Compatible programs, clawback risk, and combined funding potential

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Compatible Programs

SR&ED (federal ITC component IRAP (federal CanExport SMEs (federal Health Technology Accelerator Fund Ontario electricity support programs Ontario SR&ED provincial tax credit
Combined Funding Potential See your total funding potential

Clawback Risk

Unknown Risk
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How LSSUF Compares

Side-by-side with similar programs

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Program Amount Difficulty Payment Deadline
Life Sciences Scale-up Fund (LSSUF) Up to 33% of costs, to a max of... Hard Varies 2026 intake open June 22...
CanExport SMEs Up to $50,000 Moderate Mixed (Advance + Reimb.) Applications accepted...
Ontario Health Technology Accelerator... $1,500,000-$5,000,000 per project Moderate Lump Sum Rolling — Ontario Health...
Digital Technology Supercluster Up to $5 million Hard Reimbursement Open — Call for...
SSHRC Partnerships Up to $2.5M Hard Advance Payment Partnership Grants:...

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