Updated August 2026 · Verified against Innovation Factory / Synapse Consortium / FedDev Ontario guidelines
✓ First-Timer Friendly Milestone-Based Est. 2021
Grant Federal Active

Innovation Factory SOPHIE Commercialization Program

Innovation Factory / Synapse Consortium / FedDev Ontario
Maximum Funding
Up to $100,000
Rolling — applications reviewed continuously; program funding runs April 2024...
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Difficulty
Moderate
Payment
Milestone-Based
Trend
Stable
First-Timers
Friendly ✓
Co-Funding
44%
Innovation Factory SOPHIE Commercialization Program provides Up to $100,000 in non-dilutive FedDev Ontario funding, requiring a 1.25x applicant match in cash and in-kind. SOPHIE gives Ontario-based life science firms up to $100,000 in non-dilutive FedDev Ontario funding for a commercialization project run with a Hamilton-area academic or clinical partner — McMaster University, Mohawk College, Hamilton Health Sciences or St. The program covers up to 44% of eligible costs. Applications are accepted on an ongoing basis.
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Eligibility & Details

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Program Description

SOPHIE gives Ontario-based life science firms up to $100,000 in non-dilutive FedDev Ontario funding for a commercialization project run with a Hamilton-area academic or clinical partner — McMaster University, Mohawk College, Hamilton Health Sciences or St. Joseph's Healthcare Hamilton. The firm must match 1.25x the FedDev contribution in cash and in-kind, and identify a principal investigator or clinical champion at the partner institution. Applications are reviewed on a rolling basis.

Eligibility Requirements

  • Must be a Canadian incorporated company with operations primarily based in Ontario.
  • Must be a life science firm.
  • Must be developing an innovative technology at the TRL-6 level or above.
  • Must provide a 1.25x match as cash and in-kind contributions against the FedDev Ontario amount.
  • Must identify a principal investigator or clinical champion at the academic or clinical partner institution where the proposed project will take place.
  • The project must be a collaborative commercialization project with a Hamilton-area academic or clinical institution such as McMaster University, Mohawk College, Hamilton Health Sciences or St. Joseph's Healthcare Hamilton.
  • Applications are accepted and reviewed on a continuous, rolling basis; there is no cost to apply.
  • Funding is disbursed in stages on a reimbursement basis, so the firm must be able to carry project costs before being repaid.
Provinces
Industries
Life Sciences Research
Business Stage
Startup Growth Established

Quick Assessment

Difficulty
Moderate
Competition
Moderate
First-Timer
Friendly

Funding Details

Amount
Up to $100,000 in non-dilutive FedDev Ontario funding, requiring a 1.25x applicant match in cash and in-kind
Type
Grant
Level
Federal
Co-Funding
Up to 44% of eligible costs
Deadline
Rolling — applications reviewed continuously; program funding runs April 2024 to March 2028

Program Scorecard

Competition, effort, and approval at a glance

Competition
Moderate
Deadline
Ongoing
Approval
Varies
Accessibility
--/5
Competition
--/5
Approval Rate
--%
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Application Playbook

Step-by-step process, required documents, and expenses

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Application Steps

1 Check eligibility Confirm you are a Canadian incorporated company with operations primarily based in Ontario, developing a life science technology at TRL-6 or above, and able to provide a 1.25x cash and in-kind match.

Required Documents 9

SOPHIE application form (company information, team qualifications, company profile and technology overview, proposed project, estimated project performance metrics, marketing information)
Organization full legal name and proof of incorporation, including whether the organization is a subsidiary

Eligible Expenses 5

Ineligible Expenses 4

Intake Periods

Deadline Notes

Ineligible Organizations

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Funding Stack Strategy

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Clawback Risk

Low Risk

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How Innovation Factory SOPHIE Commercializatio... Compares

Side-by-side with similar programs

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Frequently Asked Questions

Quick answers to the questions founders most often ask about Innovation Factory SOPHIE Commercializatio...

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Do I have to put up matching funds?
Yes. SOPHIE requires a 1.25x match in cash and in-kind contributions against the FedDev Ontario amount, so a full $100,000 award means finding roughly $125,000 of your own contribution.
Do I need a hospital or university partner before I apply?
No. Apply first — the SOPHIE team reviews within 1-2 weeks and then holds an introductory meeting specifically to identify a suitable principal investigator or clinical champion for your project.
When does the money arrive?
In stages, on a reimbursement basis, against milestones set out in the SOPHIE Commercialization Project contract. You incur eligible costs first and are repaid after.
Does my company have to be in Ontario?
Yes. You must be a Canadian incorporated company with operations primarily based in Ontario, and the project must run with a Hamilton-area academic or clinical institution.
Is there an application deadline?
No. Submissions are accepted continuously and reviewed on a rolling basis. Program funding runs April 2024 to March 2028, and Innovation Factory notes reviews may take longer than usual.

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